Space: The final frontier.
These are the voyages of the Starship Harmony. Its continuing mission:
To explore strange new worlds…
To seek out new friends; new civilizations…
To boldly go where no one has gone before!

This is by far the silliest thing I've drawn yet. As soon as I had the idea to totally misinterpret this prompt, I knew I had to do something weird like this. I also had some fun with effects, as you can probably tell :)

These are the character depictions I had in mind when sketching things out:

Applejack: Jean-Luc Picard
Rainbow Dash: William T Riker
Fluttershy: Deanna Troi
Twilight Sparkle: Data
Rarity: Worf
Pinkie Pie: Wesley Crusher