Here's a list of defeated villains of 2000's 2010's and 2020's

10 Tabbu (Super Smash Bros. Brawl)

9 Toffee (Star vs The Forces of Evil)

8 Galvatron/Master Galvatron (Transformers Cybertron)

7 Midnight Sparkle (Equestria Girls Friendship Games)

6 QXR (The Special Strike Rebellion)

5 Bill Cipher (Gravity Falls)

4 Glitchtrap/Bugtrap (The Special Strike Rebellion)

3 Dr. Eggman (Sonic 2 Movie)

2 Cozy Glow, Tirek and Queen Chrysalis (MLP Friendship is Magic)

1 Darcy (Amphipia)